rs2395185, HLA-DRB9

N. diseases: 17
Disease: Adult Classical Hodgkin Lymphoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult Classical Hodgkin Lymphoma
CUI: C2347747
Disease: Adult Classical Hodgkin Lymphoma
0.010 GeneticVariation BEFREE Two novel loci associated with total cHL irrespective of EBV status were identified in the major histocompatibility complex region; one resides adjacent to MICB (rs2248462: OR = 0.61, 95% CI = 0.53 to 0.69, P = 1.3 × 10(-13)) and the other at HLA-DRA (rs2395185: OR = 0.56, 95% CI = 0.50 to 0.62, P = 8.3 × 10(-25)) with both results confirmed in an independent replication series. 22286212 2012