rs2494732, AKT1

N. diseases: 11
Disease: Cannabis use ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Cannabis use
CUI: C3160814
Disease: Cannabis use
0.040 GeneticVariation BEFREE We examined the gender and cannabis use-adjusted association between BDNF rs6265 [G>A] and AKT1 rs2494732 [T>C] and AoP. 31445421 2019
Cannabis use
CUI: C3160814
Disease: Cannabis use
0.040 GeneticVariation BEFREE Moreover, out of 6 AKT1 SNPs, rs2494732 was associated with cannabis use, but AKT1 did not mediate the effect of cannabis on BMI. 27554198 2016
Cannabis use
CUI: C3160814
Disease: Cannabis use
0.040 GeneticVariation BEFREE In a case-control study of 489 first-episode psychosis patients and 278 control subjects, we investigated the interaction between variation at the AKT1 rs2494732 single nucleotide polymorphism and cannabis use in increasing the risk of psychosis. 22831980 2012
Cannabis use
CUI: C3160814
Disease: Cannabis use
0.040 GeneticVariation BEFREE Cannabis use preceding onset of psychotic disorder did interact significantly with AKT1 rs2494732 genotype to affect CPT reaction time (β=8.0, SE 3.9, p=0.037) and CPT accuracy (β=-1.2, SE 0.4, p=0.003). 21775978 2011