rs25487, XRCC1

N. diseases: 205
Disease: Pancreatic carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pancreatic carcinoma
CUI: C0235974
Disease: Pancreatic carcinoma
0.040 GeneticVariation BEFREE In conclusion, we found that XRCC1 Arg399Gln genetic variations are associated with pa</span>ncreatic cancer development, whereas the XRCC1 Arg280His and Arg194Trp polymorphisms did not affect pancreatic cancer risk. 27323136 2016
Pancreatic carcinoma
CUI: C0235974
Disease: Pancreatic carcinoma
0.040 GeneticVariation BEFREE Therefore, the meta-analysis suggests that XRCC1 rs25487 polymorphism is associated with pancreatic cancer</span> risk in Asians. 23807675 2013
Pancreatic carcinoma
CUI: C0235974
Disease: Pancreatic carcinoma
0.040 GeneticVariation BEFREE We observed that the minor allele of rs25487 in XRCC1 was significantly associated with PC risk in the per-allele model (odds ratio = 1.29, CI = 1.01-1.65; trend P = 0.043). 22850545 2012
Pancreatic carcinoma
CUI: C0235974
Disease: Pancreatic carcinoma
0.040 GeneticVariation BEFREE We investigated the association between polymorphisms of MGMT (Leu(84)Phe and Ile(143)Val), APE1 (Asp(148)Glu), and XRCC1 (Arg(194)Trp and Arg(399)Gln) and risk of pancreatic cancer in a case-control study. 16844323 2006