rs25489, XRCC1

N. diseases: 78
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.060 GeneticVariation BEFREE However, the XRCC1 Arg399Gln and Arg280His polymorphisms were shown to have no influence on the development of gastric cancer. 27706710 2016
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.060 GeneticVariation BEFREE Our meta-analysis indicates that genetic polymorphism of the XRCC1 Arg399Gln and Arg280His do not have an association with gastric cancer risk. 25335737 2014
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.060 GeneticVariation BEFREE Our findings demonstrated that the genetic variant Arg280His in XRCC1 may contribute to cancer progression and that XRCC1 Arg194Trp variants may act as a favorable prognostic indicator of resected GC, particularly among the diffuse-type GC. 23425027 2013
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.060 GeneticVariation BEFREE The results of the overall meta-analysis did not suggest any association between Arg280His/Arg399Gln polymorphisms and GC susceptibility for all genetic models. 21604176 2012
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.060 GeneticVariation BEFREE The authors performed a systematic review and meta-analysis of associations of the x-ray repair cross-complementing 1 gene (XRCC1) single nucleotide polymorphisms (SNPs) Arg194Trp, Arg280His, and Arg399Gln with gastric cancer risk, based on eligible studies retrieved from electronic databases for the period January 2000-December 2009. 21216841 2011
Stomach Carcinoma
CUI: C0699791
Disease: Stomach Carcinoma
0.060 GeneticVariation BEFREE In our association study between three amino acid substitution polymorphisms of XRCC1 (Arg194Trp, Arg280His, and Arg399Gln) and the risk of gastric cancer in the Korean population, none of the polymorphisms were associated with increased risk of gastric cancer. 12359351 2002