rs25489, XRCC1

N. diseases: 48
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.040 GeneticVariation BEFREE However, the XRCC1 R194W and R280H polymorphisms were both associated with increased bladder cancer risk among Asians. 24039945 2014
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.040 GeneticVariation BEFREE XRCC1 Arg194Trp and Arg280His polymorphisms increase bladder cancer risk in Asian population: evidence from a meta-analysis. 23704969 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.040 GeneticVariation BEFREE Our meta-analysis results suggest that XRCC1 Arg194Trp and Arg280His polymorphisms are associated with significantly increased risk of bladder cancer in Asians. 23636799 2013
Bladder Neoplasm
CUI: C0005695
Disease: Bladder Neoplasm
0.040 GeneticVariation BEFREE We found an increased risk of bladder cancer associated with the XRCC1 194Trp/Trp and 280Arg/His genotypes (adjusted odds ratio = 3.90, 95% confidence interval = 1.69-8.98 for 194Trp/Trp and 2.53, 1.67-3.83 for 280Arg/His) compared with the 194Arg/Arg and 280Arg/Arg genotypes, respectively. 20218899 2010