rs25489, XRCC1

N. diseases: 78
Disease: Central Nervous System Neoplasms ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Central Nervous System Neoplasms
CUI: C0085136
Disease: Central Nervous System Neoplasms
0.010 GeneticVariation BEFREE Results We demonstrated an association between six previously published single nucleotide polymorphisms (rs15869 [ BRCA2], rs1805389 [ LIG4], rs8079544 [ TP53], rs25489 [ XRCC1], rs1673041 [ POLD1], and rs11615 [ ERCC1]) and subsequent CNS tumors in survivors of childhood cancer. 28976792 2017