rs25489, XRCC1

N. diseases: 48
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.040 GeneticVariation BEFREE No evidence of association of Arg194Trp (980 HCC cases and 966 controls) and Arg280His (1,200 HCC cases and 1,236 controls) with HCC risk was found. 23055199 2013
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.040 GeneticVariation BEFREE More rigorous association studies are needed to verify the involvement of XRCC1 Arg280His polymorphism in HCC susceptibility. 22919255 2013
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.040 GeneticVariation BEFREE In contrast, there was no association between HCC susceptibility and the distribution of XRCC1 His 280 His and Arg280His. 22565339 2012
Liver carcinoma
CUI: C2239176
Disease: Liver carcinoma
0.040 GeneticVariation BEFREE Interestingly, the risk for HCC was further enhanced by 35.96 (95% CI = 11.64-110.91; P < 0.001) and 5.28 times (95% CI = 2.81-9.09; P < 0.001) when the genotype Arg280His was found in association with Arg194Trp and Arg399Gln, respectively. 19194663 2009