rs25489, XRCC1

N. diseases: 78
Disease: Malignant neoplasm of colon and/or rectum ×
Source: BEFREE ×
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of colon and/or rectum
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
0.020 GeneticVariation BEFREE The Arg280His polymorphism modified the association between alcohol consumption and colorectal cancer risk (interaction P = 0.049). 22186158 2012
Malignant neoplasm of colon and/or rectum
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
0.020 GeneticVariation BEFREE No association is found between the polymorphisms in XRCC1 (Arg399Gln, Arg280His, and Arg194Trp) and risk of colorectal cancer. 20033188 2010