Disease: Alzheimer's Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.030 GeneticVariation BEFREE SLC6A4 polymorphisms are not associated with the risk of developing major psychiatric disorders (SCZ and BPD); however some signals were detected in ALC (HTTLPR p<sub>d</sub> = 9.25 × 10<sup>-03</sup>, p<sub>r</sub> = 7.24 × 10<sup>-03</sup>; rs2066713 p<sub>d</sub> = 6.35 × 10<sup>-08</sup>; rs25531 p<sub>d</sub> = 2.95 × 10<sup>-02</sup>; rs4251417 p<sub>d</sub> = 2.46 × 10<sup>-03</sup>), and ALZ (rs6354 p<sub>r</sub> = 1.22 × 10<sup>-02</sup>; rs7224199 p<sub>d</sub> = 1.00 × 10<sup>-08</sup>, p<sub>r</sub> = 2.65 × 10<sup>-02</sup>) cohorts. 31595439 2020
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.030 GeneticVariation BEFREE The distributions of 5-HTT-LPR and rs25531 polymorphisms in AD subjects were not different from those of controls. 27414430 2016
Alzheimer's Disease
CUI: C0002395
Disease: Alzheimer's Disease
0.030 GeneticVariation BEFREE We conclude that 5-HTTLPR and rs25531 are not major genetic modulators of BPSD development in AD. 19625753 2009