Disease: Post-Traumatic Stress Disorder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Post-Traumatic Stress Disorder
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
0.030 GeneticVariation BEFREE We found that although the STin2 variant and 5-HTTLPR alone did not associate with increased PTSD symptoms, rs25531 and the 5-HTTLPR multimarker genotype (combined 5-HTTLPR and rs25531) were associated with significantly increased acute stress disorder symptoms at 2 to 4 weeks postshooting (n = 161; P < .05). 21893641 2012
Post-Traumatic Stress Disorder
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
0.030 GeneticVariation BEFREE We investigated whether SLC6A4 promoter polymorphisms (5-HTTLPR, rs25531) and several downstream single nucleotide polymorphisms (SNPs) modulated activity of brain regions involved in the cognitive control of emotion in post-9/11 veterans with PTSD. 21545724 2011
Post-Traumatic Stress Disorder
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
0.030 GeneticVariation BEFREE There were significant intergroup (PTSD versus non-PTSD) differences in the genotype frequencies of 5-HTTLPR/rs25531 (χ(2) [1, n = 388] = 16.23, P = 5.62 × 10(-5) ). 21818827 2011