Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.020 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892 2019
Unipolar Depression
CUI: C0041696
Disease: Unipolar Depression
0.020 GeneticVariation BEFREE 49 patients with major depression and SSRI treatment were genotyped for the 5-HTTLPR locus including the rs25531. 22086748 2012