rs267601394, EZH2

N. diseases: 8
Disease: Adult Lymphoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Adult Lymphoma
CUI: C1332206
Disease: Adult Lymphoma
0.020 GeneticVariation BEFREE These results suggest that Ezh2(Y641F) induces lymphoma and melanoma through a vast reorganization of chromatin structure, inducing both repression and activation of polycomb-regulated loci. 27135738 2016
Adult Lymphoma
CUI: C1332206
Disease: Adult Lymphoma
0.020 GeneticVariation BEFREE As EZH2 mutations often coincide with other mutations in lymphoma, we combined the expression of EZH2(Y641F) by crossing these transgenic mice with Eµ-Myc transgenic mice. 24802772 2014