rs2740574, CYP3A4

N. diseases: 12
Disease: Pregnancy associated hypertension ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Pregnancy associated hypertension
CUI: C0852036
Disease: Pregnancy associated hypertension
0.010 GeneticVariation BEFREE The CYP3A5 genotype was related with blood pressure in the general population, but the effect on the risk for hypertension in pregnancy has not been evaluated.We compared the allele and genotype frequencies of three functional SNPs in the CYP3A5 (rs776746), CYP3A4 (rs2740574), and CYP21A2 (rs6471) genes between pregnant women who developed hypertension (n = 250) or who remained normotensive (control group, n = 250). 20617557 2010