rs281875215, CARD14

N. diseases: 6
Disease: PSORIASIS 2 ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
PSORIASIS 2
CUI: C1864497
Disease: PSORIASIS 2
0.800 GeneticVariation UNIPROT The paracaspase MALT1 mediates CARD14-induced signaling in keratinocytes. 27113748 2016
PSORIASIS 2
CUI: C1864497
Disease: PSORIASIS 2
0.800 GeneticVariation UNIPROT Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation. 27071417 2016
PSORIASIS 2
CUI: C1864497
Disease: PSORIASIS 2
0.800 GeneticVariation UNIPROT CARD14 alterations in Tunisian patients with psoriasis and further characterization in European cohorts. 26358359 2016
PSORIASIS 2
CUI: C1864497
Disease: PSORIASIS 2
0.800 GeneticVariation UNIPROT Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis. 22521419 2012
PSORIASIS 2
CUI: C1864497
Disease: PSORIASIS 2
0.800 GeneticVariation UNIPROT PSORS2 is due to mutations in CARD14. 22521418 2012
PSORIASIS 2
CUI: C1864497
Disease: PSORIASIS 2
0.800 CausalMutation CLINVAR