rs28934575, TP53

N. diseases: 37
Disease: Malignant neoplasm of liver ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of liver
CUI: C0345904
Disease: Malignant neoplasm of liver
0.010 GeneticVariation BEFREE The mutation Arg114Gly was predicted bioinformatically to affect Nogo-66 dimensional structure of Nogo-C. Our previous works also had indicated that mutant Nogo-C promoted liver cancer cell line apoptosis and resulted in molecular marker of HCC p53 gene transfer from nucleus to cytoplast. 18080785 2009