rs28934576, TP53

N. diseases: 78
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Neoplasm Metastasis
CUI: C0027627
Disease: Neoplasm Metastasis
0.020 GeneticVariation BEFREE Together, these results reveal an important role for DLX2-NRP2 in p53-R273H</span>-induced cell mobility and tumor metastasis. 28796261 2017
Neoplasm Metastasis
CUI: C0027627
Disease: Neoplasm Metastasis
0.020 GeneticVariation BEFREE Taken together, these results suggest that transdominance of R273H mutant over wt p53 rather than a gain-of-function promotes tumor metastasis by increasing invasion and migration in HHUA cells. 17636407 2007