|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Analysis of the data based on race revealed that rs2910164 (miR-146a) polymorphism may decrease the risk of CRC among Europeans, in a co dominant model [OR = 0.81, 95% CI 0.66-0.99, p = 0.04], but not among Asians.
|
30447914 |
2018 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Hsa-mir-149C/T rs2292832 and hsa-mir-146a G/C rs2910164 may influence CRC risk in an ethnicity-dependent manner by interfering with CRC progression parameters in Tunisian cohort.
|
29715515 |
2018 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our study provides evidence that miR-146a rs2910164 polymorphism may play an important role in susceptibility to CRC in Chinese male population.
|
29578157 |
2018 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
However, the association of six polymorphisms (miR-608 rs4919510, miR-499a rs3746444, miR-146a rs2910164, pre-miR-143 rs41291957, pre-miR-124-1 rs531564 and pre-miR-26a-1 rs7372209) with colorectal cancer (CRC) risk, therapeutic response and survival remains unclear.
|
27713147 |
2016 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
miR-146a Polymorphism (rs2910164) Predicts Colorectal Cancer Patients' Susceptibility to Liver Metastasis.
|
27824903 |
2016 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis showed that rs2910164 and rs2292832 may increase the risk of CRC.
|
26078942 |
2015 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our findings suggest that the rs2910164 polymorphism in pre-miRNA, miR-146a may be associated with the risk of CRC.
|
25519012 |
2015 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our current meta-analysis demonstrates that miR-196a2 rs11614913 most likely contributes to decreased risk of CRC, whereas miR-146a rs2910164 may not be associated with the susceptibility to CRC.
|
24399071 |
2014 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We found that the miR-146a polymorphism rs2910164 might significantly increase the susceptibility of digestive tumors, in particular for esophageal cancer and colorectal cancers.
|
24247819 |
2014 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
MiR-146a (rs2910164 G > C) polymorphism is associated with CRC susceptibility and histological differentiation in Chinese Han population.
|
24136745 |
2014 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
We then conducted a population-based case-control study which included 554 colorectal cancer cases and 566 matched healthy controls to assess the association of a genetic variant (rs2910164) in miR-146a with colorectal cancer susceptibility.
|
24740563 |
2014 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results indicated that there was no association between miR-146a G/C rs2910164 polymorphism and CRC risk either in the overall analysis or among Asians, when stratified on the basis of ethnicity.
|
25283877 |
2014 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
These findings suggest that rs11614913 and rs2910164 polymorphisms may be associated with the etiology of CRC.
|
23728616 |
2013 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, our results suggest that miR-146a rs2910164 may contribute to the susceptibility to CRC in a Chinese population.
|
23306950 |
2013 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
A miR-146a polymorphism (rs2910164) predicts risk of and survival from colorectal cancer.
|
23898084 |
2013 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our data suggest a lack of association between rs11614913, rs895819 and rs2910164 and colorectal cancer risk in the Central-European Caucasian population, a population with an extremely high incidence of sporadic colorectal cancer.
|
22719192 |
2012 |
|
Colorectal Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Although recent studies focused on various diseases that harbor the miR-146aC>G (rs2910164), 149C>T (rs2292832), 196a2C>T (rs11614913), and 499A>G (rs3746444) polymorphisms, the role of miRNA genetic variants in colorectal cancer is still unknown.
|
22161766 |
2012 |