Behcet Syndrome
|
|
0.710 |
GeneticVariation
|
BEFREE |
Our findings not only confirmed the association of IL10/rs1800871 and IL23R-IL12RB2/rs924080 with BD but also identified 2 susceptibility single nucleotide polymorphisms in IL10 and IL23R-IL12RB2 (rs3024490 and rs12141431) with BD in Han Chinese.
|
27464962 |
2017 |
Behcet Syndrome
|
|
0.710 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.
|
23291587 |
2013 |
Nephritis, Interstitial
|
|
0.010 |
GeneticVariation
|
BEFREE |
The homozygous minor allele in IL-10 +434T (rs2222202) and IL-10+504G (rs3024490) was found in all patients with TIN or TINU syndrome while the frequency of these minor alleles in the control population was 44% and 23%, respectively (p <0.001).
|
30779760 |
2019 |
Tubulointerstitial nephritis and uveitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The homozygous minor allele in IL-10 +434T (rs2222202) and IL-10+504G (rs3024490) was found in all patients with TIN or TINU syndrome while the frequency of these minor alleles in the control population was 44% and 23%, respectively (p <0.001).
|
30779760 |
2019 |
Nephritis, Tubulointerstitial
|
|
0.010 |
GeneticVariation
|
BEFREE |
The homozygous minor allele in IL-10 +434T (rs2222202) and IL-10+504G (rs3024490) was found in all patients with TIN or TINU syndrome while the frequency of these minor alleles in the control population was 44% and 23%, respectively (p <0.001).
|
30779760 |
2019 |
Metabolic Syndrome X
|
|
0.010 |
GeneticVariation
|
BEFREE |
Individuals with and without MetS were compared according to their plasma inflammatory biomarkers, fatty acid profile, and genotype frequency of the IL1B (rs16944, rs1143623, rs1143627, rs1143634 and rs1143643), IL6 (rs1800795, rs1800796 and rs1800797) and IL10 (rs1554286, rs1800871, rs1800872, rs1800890 and rs3024490) genes SNP.
|
28268030 |
2018 |
Cerebral Palsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
IL-10 polymorphisms and protein association analysis showed that the TT genotype had higher plasma IL-10 protein levels compared to the GG + GT genotype at rs3024490 (11.14 ± 7.27 vs. 7.44 ± 6.95 pg/ml, <i>p</i> = 0.045, respectively) in CP cases.
|
29623066 |
2018 |
Tuberculosis, Pulmonary
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found correlations between one SNP in IL6 (rs2069837 <i>p</i> = 6.63E-11), seven SNPs in <i>IL10</i> (rs1554286 <i>p</i> = 6.87E-20, rs1518111 <i>p</i> = 6.11E-11, rs3021094 <i>p</i> = 6.75E-29, rs3790622 <i>p</i> = 2.40E-06, rs3024490 <i>p</i> = 6.73E-11, rs1800872 <i>p</i> = 6.18E-11, rs1800871 <i>p</i> = 6.73E-11) and incidences of PTB.
|
29662655 |
2018 |
Ankylosing spondylitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
IL10 rs1878672 and rs3024490 polymorphisms obviously increase the susceptibility to AS, but not TNF-α rs3093662.
|
26823867 |
2015 |
Hepatitis B
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study found that rs3024490 G/T allele, located in the intron 1 region and highly prevalent in Chinese populations, was significantly different between the chronic HBV infection cases and the acute infection controls in single allele analysis, genetic models analysis, and haplotypes analysis.
|
24631780 |
2014 |
Hepatitis B, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
This suggested that the rs3024490 within IL-10 was associated with susceptibility to chronic hepatitis B in a Chinese Han population.
|
24631780 |
2014 |
Uveitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The results demonstrate that uveitis is associated with three haplotype-tagging SNPs (htSNPs) in the IL10 gene: htSNP2 (rs6703630), htSNP5 (rs2222202), and htSNP6 (rs3024490).
|
20335604 |
2010 |