Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.050 GeneticVariation BEFREE The genotype distribution in HBV carriers relative to those who resolved HBV showed that rs3077 and rs9277378 were significantly associated with protective effects against CHB in minor dominant model (OR = 0.45, p<0.001 and OR = 0.47, p<0.001). 24465836 2014
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.050 GeneticVariation BEFREE There was no significant association between HLA-DP polymorphism (rs3077) and IFN-γ receptor-2 gene polymorphism (rs2284553) with viral activity in HBeAg-negative CHB patients. 23980639 2014
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.050 GeneticVariation BEFREE However, no significant association was seen for rs3077 with progressive CHB infection versus inactive HBsAg carrier status (OR = 2.7, 95% CI: 0.6-11.1; p = 0.31). 22448225 2012
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.050 GeneticVariation BEFREE We also found that the HLA-DPA1 and HLA-DPB1 genes were significantly associated with protective effects against chronic hepatitis B (CHB) in Japanese, Korean and other Asian populations, including Chinese and Thai individuals (P(meta) = 4.40×10⁻¹⁹ for rs3077 and P(meta) = 1.28×10⁻¹⁵ for rs9277542). 22737229 2012
Complete atrioventricular block
CUI: C0151517
Disease: Complete atrioventricular block
0.050 GeneticVariation BEFREE Association of CHB with SNPs rs2856718 and rs7453920 remains significant even after stratification with rs3077 and rs9277535, indicating independent effect of HLA-DQ variants on CHB susceptibility (P-value of 1.52 × 10(-21)- 2.38 × 10(-30)). 21750111 2011