rs3129878, HLA-DRA

N. diseases: 6
Disease: Non-obstructive azoospermia ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Non-obstructive azoospermia
CUI: C4021107
Disease: Non-obstructive azoospermia
0.720 GeneticVariation BEFREE The case-control study strongly suggested a significant association between loci rs3129878, rs498422 and rs7194 and NOA (P = 6.75 × 10<sup>-21</sup> (OR = 2.2586), P = 0.0060 (OR = 1.4013) and P = 0.0128 (OR = 1.2626) respectively). 27597543 2017
Non-obstructive azoospermia
CUI: C4021107
Disease: Non-obstructive azoospermia
0.720 GeneticVariation BEFREE Interestingly, the normozoospermic males with the risk genotypes of rs12097821 and rs3129878 + rs10842262 + rs12097821 were observed to have higher total sperm counts relative to non-risk genotypes, suggesting that the risk alleles of the genetic loci may not be via impairing spermatogenic ability to express susceptibility to NOA. 25505198 2015
Non-obstructive azoospermia
CUI: C4021107
Disease: Non-obstructive azoospermia
0.720 GeneticVariation GWASDB A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia. 22541561 2012