rs3218536, XRCC2

N. diseases: 37
Disease: ovarian neoplasm ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.050 GeneticVariation BEFREE In conclusion, this meta-analysis indicates that XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms may not be associated with the risk of OC. 27863412 2016
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.050 GeneticVariation BEFREE Overall, a significant association was found between the Arg188His polymorphism and ovarian cancer risk when all studies were pooled into the meta-analysis (Arg/Arg vs His/His: OR = 1.85, 95%CI = 1.15-3.00; Arg/Arg vs Arg/His: OR = 1.17, 95%CI = 1.03-1.32; dominant model: OR = 0.84, 95%CI = 0.74-0.95; recessive model: OR = 1.69, 95%CI = 1.05-2.70). 26400309 2015
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.050 GeneticVariation BEFREE Interestingly, XRCC2 G>A (rs3218536) polymorphism might reduce the risk of ovarian cancer. 24599673 2014
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.050 GeneticVariation BEFREE The current meta-analysis indicated that the Arg188His polymorphism in the XRCC2 gene might be a risk factor for ovarian cancer. 24414483 2014
ovarian neoplasm
CUI: C0919267
Disease: ovarian neoplasm
0.050 GeneticVariation BEFREE The aim of the present study was to evaluate the role of SNPs in three genes, XRCC2 (R188H), ERCC2 (K751Q) and CDKN1B (V109G) which are with moderate risk for ovarian cancer susceptibility in Egyptian women. 23277402 2013