rs324011, STAT6

N. diseases: 12
Disease: Asthma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE A case-control study for association of STAT6 polymorphisms rs4559 and rs324011 with asthma risk was performed. 30511616 2018
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE Both overall and subgroup analyses indicated no effect of rs324011 on asthma risk. 24952213 2014
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE By the contrast of alleles tests, no significant differences between asthma and healthy groups were detected for both variants (rs324011: X(2)=0.25, Pearson's P-value=0.617; rs324015: X(2)=0.068, Pearson's P=0.814).When testing for genotypes, rs324011 homozygous T/T genotype was significantly associated with asthma, when the Recessive model is considered (T/T vs. C/C+C/T) (adjusted, OR=2.49, 95% CI=1.18-5.25, Pearson's P=0.014(∗), Yates' P=0.022(∗)). 24912007 2014
Asthma
CUI: C0004096
Disease: Asthma
0.040 GeneticVariation BEFREE No association was detected between the STAT6 polymorphism rs324011 or the TBXA2R polymorphisms rs8113232 and rs3786989 and asthma susceptibility. 22017802 2012