rs324420, FAAH

N. diseases: 48
Disease: Obesity ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE This may explain the greater vulnerability for addiction and obesity in individuals with C385A genetic variant and by extension, suggest that a D3 antagonism strategy in substance use disorders should consider FAAH C385A polymorphism. 31775159 2020
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE The influence of the fatty acid amide hydrolase 385C>A single nucleotide polymorphisms on obesity susceptibility. 31286394 2019
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE The FAAH SNP rs324420 was associated with increased obesity (three studies). 30129173 2019
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE It has been demonstrated that the polymorphism 385 C/A of FAAH (fatty acid amide hydrolase) was associated with obesity and metabolic disorders. 22609216 2013
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE As we observed some evidence for an association of the FAAH variants rs2295632 rs324420 with early onset but not adult obesity, we conclude that the FAAH variants analyzed here at least do not seem to play a major role in the etiology of obesity within our samples. 20044928 2010
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE It has been demonstrated that the polymorphism 385 C/A of fatty acid amide hydrolase was associated with obesity. 20102775 2010
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE The aim of our study was to investigate the relationship of polymorphism (cDNA 385 C-->A) of FAAH gene on obesity parameters in patients with diabetes mellitus type 2. 20056290 2010
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE An association between Pro129Thr variant of the FAAH gene and obesity has been described, but various studies have yielded conflicting results. 18819056 2008
Obesity
CUI: C0028754
Disease: Obesity
0.090 GeneticVariation BEFREE Our results in 5,109 subjects suggest that FAAH Pro129Thr polymorphism may modestly contribute to class III adult obesity in the French population. 20054193 2008