Disease: Alcohol Use Disorder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Alcohol Use Disorder
CUI: C0001956
Disease: Alcohol Use Disorder
0.020 GeneticVariation BEFREE In recent years, accumulating data from various labs have demonstrated an A/T single-nucleotide polymorphism (SNP) resulting in (Asn107Ile) switch in the human NPSR gene as the risk factor for various psychiatric disorders such as panic disorder, post traumatic syndrome, alcohol use disorders and enhanced anxiety sensitivity, although, this is in stark contrast to the findings made in animal models which have consistently projected the anxiolytic nature of this peptide system. 26680586 2016
Alcohol Use Disorder
CUI: C0001956
Disease: Alcohol Use Disorder
0.020 GeneticVariation BEFREE In the general population, the NPSR1 Asn(107) Ile polymorphism is associated with AUD and alcohol consumption, dependent on sex, environment and age. 24754478 2015