rs34637584, LRRK2

N. diseases: 78
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Bradykinesia
CUI: C0233565
Disease: Bradykinesia
0.020 GeneticVariation BEFREE Two cohorts of G2019S KI mice and wild-type littermates (WT) were subjected to behavioral tests, specific for akinesia, bradykinesia and overall gait ability, at different ages (3, 6, 10, 15 and 19months). 25107341 2014
Bradykinesia
CUI: C0233565
Disease: Bradykinesia
0.020 GeneticVariation BEFREE More LRRK2 G2019S carriers reported muscle stiffness (rigidity, p = 0.007) and balance disturbances (p = 0.008), while more GBA mutation carriers reported slowness (bradykinesia, p = 0.021). 19458969 2010