rs34637584, LRRK2

N. diseases: 78
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Depressed mood
CUI: C0344315
Disease: Depressed mood
0.030 GeneticVariation BEFREE The G2019S mutation in leucine-rich repeat kinase 2 (<i>LRRK2</i>) is a prevalent cause of late-onset Parkinson's disease, producing psychiatric and motor symptoms, including depression, that are indistinguishable from sporadic cases. 30249796 2018
Depressed mood
CUI: C0344315
Disease: Depressed mood
0.030 GeneticVariation BEFREE Cognitive impairment and depression were less common in G2019S male carriers compared with females. 29989150 2018
Depressed mood
CUI: C0344315
Disease: Depressed mood
0.030 GeneticVariation BEFREE We identified one heterozygous G2019S mutation in a PD patient who also suffered from obsessive disorder and depression and presented hallucinations and delusional jealousy while he was treated with l-dopa, pramipexole, and amantadine. 18621566 2009