rs34637584, LRRK2

N. diseases: 78
Disease: Lewy Body Disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lewy Body Disease
CUI: C0752347
Disease: Lewy Body Disease
0.030 GeneticVariation BEFREE Thirty-five consecutively recruited AJ patients with newly diagnosed clinically probable or possible DLB underwent genotyping for the 7 known AJ GBA mutations and the LRRK2 G2019S mutation. 27723861 2016
Lewy Body Disease
CUI: C0752347
Disease: Lewy Body Disease
0.030 GeneticVariation BEFREE LRRK2 does not appear to play a major role in DLB, however further study of p.G2019S and the p.N551K-R1398H-K1423K haplotype is warranted to better understand their involvement in determining DLB risk. 27521182 2016
Lewy Body Disease
CUI: C0752347
Disease: Lewy Body Disease
0.030 GeneticVariation BEFREE Lrrk2 G2019S was observed in approximately 2% (n = 8) of our Parkinson's disease/Lewy body disease cases (n = 405). 16437559 2006