rs34677591, SDHD;TIMM8B

N. diseases: 12
Disease: Primary differentiated carcinoma of thyroid gland ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Primary differentiated carcinoma of thyroid gland
CUI: C4722172
Disease: Primary differentiated carcinoma of thyroid gland
0.010 GeneticVariation BEFREE Our current study shows that SDHD-G12S and -H50R variants cause down-regulation of autophagy, demonstrating a role for SDHD in autophagy-associated pathogenesis of differentiated thyroid cancer. 28164237 2017