Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.710 GeneticVariation GWASCAT Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases. 30573655 2019
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.710 GeneticVariation GWASCAT Transethnic meta-analysis identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. 28314753 2017
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.710 GeneticVariation GWASCAT Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis. 24387989 2014
Systemic Scleroderma
CUI: C0036421
Disease: Systemic Scleroderma
0.710 GeneticVariation BEFREE This study identified a likely functional variant influencing scleroderma susceptibility at the DNASE1L3 locus; a missense polymorphism rs35677470 in DNASE1L3, with an odds ratio of 2.35 (P = 2.3 × 10(-10)) in anti-centromere antibody (ACA) positive cases. 25332064 2014