rs3745274, CYP2B6

N. diseases: 30
Disease: CYP2B6 polymorphism ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
CYP2B6 polymorphism
CUI: C3665815
Disease: CYP2B6 polymorphism
0.030 GeneticVariation BEFREE The post-menopausal status was related to high levels of asthenia in docetaxel protocol whereas CYP2B6 polymorphism (rs3745274) was related to high levels in FAC protocol. 31056713 2020
CYP2B6 polymorphism
CUI: C3665815
Disease: CYP2B6 polymorphism
0.030 GeneticVariation BEFREE The aim of this study was to evaluate the clinical and economic impact of efavirenz (EFV) dose adjustment by monitoring plasma concentrations and pharmacogenetic analysis of the 516G>T CYP2B6 polymorphism. 24956253 2014
CYP2B6 polymorphism
CUI: C3665815
Disease: CYP2B6 polymorphism
0.030 GeneticVariation BEFREE Previous studies outside of the United Kingdom have shown associations between the CYP2B6 polymorphism G516T and increased toxicity. 19486190 2009