|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
The minor allele for RA susceptibility, rs3761847 SNP in TRAF1/C5 region, was associated with a poor response in linear and logistic univariate and multivariate regression analyses.
|
25834819 |
2015 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
This meta-analysis confirms that the TRAF1-C5 rs10818488, rs3761847, rs2900180 and rs10760130 polymorphisms are associated with RA susceptibility in Europeans.
|
24144456 |
2014 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
GWASDB |
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
|
23143596 |
2012 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
This significant association between rs3761847 and RA was independent of the concentrations of anti-CCP and RF.
|
21492465 |
2011 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
GWASCAT |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
20453842 |
2010 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
Interestingly, alleles rs3761847 A and rs10818488 G had increased the risk for RA in the present study, while they decreased the risk in the original studies.
|
19336421 |
2010 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
GWASDB |
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
|
20453842 |
2010 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
Our results demonstrate that within and around TRAF1, excluding PHF19 and C5, SNPs highly correlated with rs7021206, but not those correlated with rs3761847, are associated with RA in both Asians and Caucasians and are possibly correlated with causative variations.
|
19714643 |
2009 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
The risk of death in RA is increased in TRAF1/C5 rs3761847 GG homozygotes and appears to be independent of RA activity and severity as well as comorbidities relevant to CVD.
|
19116907 |
2009 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
BEFREE |
No statistically significant association of TRAF1/C5 SNPs rs3761847 and rs10818488 with RA was detected.
|
19445664 |
2009 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
Rheumatoid Arthritis
|
|
0.870 |
GeneticVariation
|
GWASCAT |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
Immune System Diseases
|
|
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
|
Autoimmune Diseases
|
|
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci.
|
21383967 |
2011 |
|
Multiple Sclerosis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
|
Epilepsy
|
|
0.010 |
GeneticVariation
|
BEFREE |
The rs3761847 SNP was associated with epilepsy under a dominant model, whereas rs10818488 was associated with CSF cellularity and parasite load under dominant and recessive models, respectively.
|
31570557 |
2019 |
|
Neurocysticercosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
This work aimed to study the possible relevance for human neurocysticercosis of single nucleotide polymorphisms (SNPs) in the C5-<i>TRAF1</i> region (rs17611 <i>C/T</i>, rs992670 <i>G/A</i>, rs25681 <i>G/A</i>, rs10818488 <i>A/G</i>, and rs3761847 <i>G/A</i>) in a Mexican population and associated with clinical and radiological traits related to neurocysticercosis severity (cell count in the cerebrospinal fluid [CSF cellularity], parasite location and parasite load in the brain, parasite degenerating stage, and epilepsy).
|
31570557 |
2019 |
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
The authors conducted meta-analyses on associations between polymorphisms of the TNFSF4 (rs2205960, rs1234315, rs10489265) and TRAF1-C5 (rs10818488, rs3761847) genes and SLE susceptibility, using fixed and random effects models.
|
22820624 |
2012 |
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
The risk of death in RA is increased in TRAF1/C5 rs3761847 GG homozygotes and appears to be independent of RA activity and severity as well as comorbidities relevant to CVD.
|
19116907 |
2009 |