Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation BEFREE Among them, CETP (rs3764261/rs2303790) and ABCG1 (rs57137919) were the major susceptibility genes for PCV in Asian population and ABCG1 (rs57137919) showed allelic diversity between PCV and AMD. 29977615 2018
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation BEFREE Our study identified two polymorphisms with a higher risk of AMD development (rs5882 and rs708272) and a protective polymorphism for AMD (rs3764261). 28918250 2017
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation BEFREE This meta-analysis revealed that both CETP rs3764261 and LIPC rs10468017 polymorphisms were significantly associated with AMD risk. 26503844 2015
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation BEFREE Our data suggested that the allele A in rs3764261 in CETP gene may be associated with a decreased risk of advanced AMD in Chinese population. 24498989 2015
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation BEFREE The SNP rs3764261 in the cholesteryl ester transfer protein (CETP) gene was associated significantly with neovascular AMD (P = 1.82×10(-4); odds ratio [OR], 1.89) and PCV (P = 4.04×10(-4); OR, 1.80). 24393350 2014
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation BEFREE After multivariate adjustment for age, sex, educational level, smoking, BMI, lipid-lowering medication use, cardiovascular disease and diabetes, and for all relevant genetic polymorphisms (ApoE2, ApoE4, CFH Y402H, ARMS2 A69S, LIPC rs10468017, LIPC rs493258, LPL rs12678919, ABCA1 rs1883025 and CETP rs3764261), higher HDL was significantly associated with an increased risk of early (OR = 2.45, 95%CI: 1.54-3.90; P = 0.0002) and any AMD (OR = 2.29, 95%CI: 1.46-3.59; P = 0.0003). 24608419 2014
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation GWASCAT Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. 21665990 2011
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation GWASDB Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. 21665990 2011
Age related macular degeneration
CUI: C0242383
Disease: Age related macular degeneration
0.860 GeneticVariation GWASDB Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. 20385819 2010