rs3764880, TLR8-AS1;TLR8

N. diseases: 11
Disease: Tuberculosis ×
Source: BEFREE ×
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.020 GeneticVariation BEFREE The A-allele of TLR8 rs3764880 SNP was protective against the development of TB in males (A vs G, OR = 0.58, 95%CI = 0.37-0.91). 30424735 2018
Tuberculosis
CUI: C0041296
Disease: Tuberculosis
0.020 GeneticVariation BEFREE We found that four polymorphisms in the TLR8 gene on chromosome X showed evidence of association with TB susceptibility in males, including a non-synonymous polymorphism rs3764880 (Met1Val; P = 0.007, odds ratio (OR) = 1.8, 95% c.i.= 1.2-2.7). 18927625 2008