rs3775291, TLR3

N. diseases: 51
Disease: Geographic Atrophy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Geographic Atrophy
CUI: C1536085
Disease: Geographic Atrophy
0.030 GeneticVariation BEFREE TLR3 rs3775291 was associated with both geographic atrophy (GA) and neovascular AMD (nAMD), with marginally significant pooled-P values. 26796995 2016
Geographic Atrophy
CUI: C1536085
Disease: Geographic Atrophy
0.030 GeneticVariation BEFREE Toll-like receptor 3 C1234T may protect against geographic atrophy through decreased dsRNA binding capacity. 21712495 2011
Geographic Atrophy
CUI: C1536085
Disease: Geographic Atrophy
0.030 GeneticVariation BEFREE The Phe variant (encoded by the T allele at rs3775291) was associated with protection against geographic atrophy (P=0.005). 18753640 2008