rs3813946, CR2

N. diseases: 5
Disease: Lupus Vulgaris ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Lupus Vulgaris
CUI: C0024131
Disease: Lupus Vulgaris
0.020 GeneticVariation BEFREE These data confirm the effects of rs3813946 on CR2 transcription, identifying the 5' UTR to be a novel regulatory element for the CR2 gene in which variation may alter gene function and modify the development of lupus. 22673213 2012
Lupus Vulgaris
CUI: C0024131
Disease: Lupus Vulgaris
0.020 GeneticVariation BEFREE Single-nucleotide polymorphism 1 (rs3813946), located in the 5' untranslated region of the CR2 gene, altered transcriptional activity, suggesting a potential mechanism by which CR2 could contribute to the development of lupus. 17360460 2007