rs387907264, PFN1

N. diseases: 5
Disease: Motor neuron atrophy ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Motor neuron atrophy
CUI: C4024896
Disease: Motor neuron atrophy
0.010 GeneticVariation BEFREE Very recently, the C71G-PFN1 has been demonstrated to cause ALS by a gain of toxicity and the acceleration of motor neuron degeneration preceded the accumulation of its aggregates. 28847504 2017