|
Lupus Erythematosus, Systemic
|
|
0.030 |
GeneticVariation
|
BEFREE |
We genotyped FcγRIIIa-158V/F (rs396991) using a pyro-sequencing assay (PSQ 96MA) in a total of 732 individuals with SLE (390 lupus nephritis and 342 non-lupus nephritis) and 886 controls.
|
24131500 |
2013 |
|
Lupus Erythematosus, Systemic
|
|
0.030 |
GeneticVariation
|
BEFREE |
To gain further insight into the role of FcgammaR polymorphisms in the genetic predisposition of SLE, association of FcgammaRIIa-H131R, IIb-I232T, IIIa-F176V and IIIb-NA1/NA2 (HNA-1a/1b) polymorphisms with SLE was analyzed in the Thai population, using case-control association analysis.
|
12753656 |
2003 |
|
Lupus Erythematosus, Systemic
|
|
0.030 |
GeneticVariation
|
BEFREE |
In a large case-control replication study of 438 patients with SLE and 219 controls, FcgammaRIIIA provided the strongest evidence of an FcgammaR-SLE association (additive model: V/V 176 versus V/F 176 OR 1.51, V/V 176 versus F/F 176 OR 1.98, P = 0.007).
|
12209518 |
2002 |
|
Peri-Implantitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
According to the results of this study, the FCGRIIa (rs1801274), FCGRIIIa (rs396991), and FCGRIIIb (rs1050501) polymorphisms were significantly associated with CP and peri-implantitis and may have a role in the pathogenesis of these diseases.
|
30887566 |
2019 |
|
Chronic Periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
According to the results of this study, the FCGRIIa (rs1801274), FCGRIIIa (rs396991), and FCGRIIIb (rs1050501) polymorphisms were significantly associated with CP and peri-implantitis and may have a role in the pathogenesis of these diseases.
|
30887566 |
2019 |
|
HIV Infections
|
|
0.010 |
GeneticVariation
|
BEFREE |
The study underscores the role of polymorphism in the FcγRIIIa receptor on HIV-specific ADCC response and suggests that the screening of the individuals for FcγRIIIa-V176F and Y158H polymorphisms could be useful for prediction of efficient treatment in monoclonal antibody-based therapies aimed at ADCC in HIV infection.
|
31842762 |
2019 |
|
Malaria
|
|
0.010 |
GeneticVariation
|
BEFREE |
Differences in the allelic frequencies of rs3933769 and rs396991 among Fulani and Dogon indirectly suggest that these SNPs may influence malaria susceptibility and pathogenesis in the study population.
|
26785902 |
2016 |
|
Guillain-Barre Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
We assessed whether polymorphisms rs1801274 in FCGR2A and rs396991 in FCGR3A were associated with GBS in a Brazilian population.
|
27609290 |
2016 |
|
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We conducted a meta-analysis on the association between FCGR2A H131R (rs1801274), FCGR3A F158V (rs396991), and FCGR3B NA1/NA2 polymorphisms and RA susceptibility.
|
26314337 |
2015 |
|
Asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, variants of activating FcγRIIIA (rs396991), and FcγRIIIB (NA1 and NA2), and FcγRIIC (rs10917661) are not associated with asthma, BHR, and atopy (P>0.05).
|
24586589 |
2014 |
|
Periodontitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We did a literature search using PubMed and Embase, and conducted a meta-analysis on the associations between the FCGR2A H131R (rs1801274), FCGR3A F158V (rs396991), and FCGR3B NA1/NA2 polymorphisms and periodontitis using allele contrast, the recessive model, the dominant model, and the homozygote contrast.
|
23649770 |
2013 |
|
Lupus Nephritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We genotyped FcγRIIIa-158V/F (rs396991) using a pyro-sequencing assay (PSQ 96MA) in a total of 732 individuals with SLE (390 lupus nephritis and 342 non-lupus nephritis) and 886 controls.
|
24131500 |
2013 |
|
Autoimmune Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
These results suggest that FCGR3A-158F/V (rs396991) gene polymorphism play a role in the response to rituximab in autoimmune diseases.
|
23075294 |
2012 |
|
Meniere Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, no differences were found in genotype frequencies for rs396991 between patients with MD and controls from Galicia (CATT, p = 0.14).
|
21208440 |
2011 |
|
Low Grade Squamous Intraepithelial Neoplasia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The distribution of the polymorphism V158F (rs396991) in FcGR3A in cervical smears was detected in a group of 84 women with stable or regressed low-grade squamous intraepithelial lesions (group I) and a group of 54 women with high-grade squamous intraepithelial lesions (HSIL) (group II).
|
20018222 |
2010 |
|
High-Grade Squamous Intraepithelial Lesions
|
|
0.010 |
GeneticVariation
|
BEFREE |
The distribution of the polymorphism V158F (rs396991) in FcGR3A in cervical smears was detected in a group of 84 women with stable or regressed low-grade squamous intraepithelial lesions (group I) and a group of 54 women with high-grade squamous intraepithelial lesions (HSIL) (group II).
|
20018222 |
2010 |