rs397517132, EGFR

N. diseases: 48
Disease: Colonic Neoplasms ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Colonic Neoplasms
CUI: C0009375
Disease: Colonic Neoplasms
0.020 GeneticVariation BEFREE A CIMP(+)/BRAF(V600E)/MLH1(-) phenotype was found in 3/4 right colon tumors. 24503755 2014
Colonic Neoplasms
CUI: C0009375
Disease: Colonic Neoplasms
0.020 GeneticVariation BEFREE To investigate the cause of the limited therapeutic effect of PLX4032 in BRAF(V600E) mutant colon tumours, here we performed an RNA-interference-based genetic screen in human cells to search for kinases whose knockdown synergizes with BRAF(V600E) inhibition. 22281684 2012