|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.
|
12360400 |
2002 |
|
Mammary Neoplasms
|
|
0.700 |
CausalMutation
|
CLINVAR |
Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients.
|
27257965 |
2016 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Mechanisms of BRCA1 tumor suppression.
|
22843421 |
2012 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
A high incidence of BRCA1 mutations in 20 breast-ovarian cancer families.
|
8554067 |
1996 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Founder mutations in BRCA1 and BRCA2 genes.
|
17591843 |
2007 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Founder mutations in BRCA1 and BRCA2 genes.
|
17591843 |
2007 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
CLINVAR |
BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.
|
12360400 |
2002 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Non-founder BRCA1 mutations in Russian breast cancer patients.
|
20727672 |
2010 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Breast and ovarian cancer predisposition due to de novo BRCA1 and BRCA2 mutations.
|
26028024 |
2016 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.
|
11739404 |
2001 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Sensitivity of BRCA1/2 mutation testing in 466 breast/ovarian cancer families.
|
12960223 |
2003 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Average age-specific cumulative risk of breast cancer according to type and site of germline mutations in BRCA1 and BRCA2 estimated from multiple-case breast cancer families attending Australian family cancer clinics.
|
12601471 |
2003 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.
|
10486320 |
1999 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Efficiency of BRCAPRO and Myriad II mutation probability thresholds versus cancer history criteria alone for BRCA1/2 mutation detection.
|
19949876 |
2010 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
BRCA1, BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives.
|
16644204 |
2006 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients.
|
27553291 |
2016 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.
|
10486320 |
1999 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Prevalence of BRCA1 and BRCA2 germline mutations in patients with triple-negative breast cancer.
|
25682074 |
2015 |
|
Neoplastic Syndromes, Hereditary
|
|
0.700 |
CausalMutation
|
CLINVAR |
Prevalence of BRCA1 and BRCA2 mutations in Pakistani breast and ovarian cancer patients.
|
16998791 |
2006 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
CLINVAR |
A high incidence of BRCA1 mutations in 20 breast-ovarian cancer families.
|
8554067 |
1996 |
|
Malignant neoplasm of breast
|
|
0.700 |
CausalMutation
|
CLINVAR |
|
|
|
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer.
|
17688236 |
2007 |
|
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
|
|
0.700 |
GeneticVariation
|
CLINVAR |
Prevalence of BRCA1 and BRCA2 mutations in Pakistani breast and ovarian cancer patients.
|
16998791 |
2006 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Clinical classification of BRCA1 and BRCA2 DNA sequence variants: the value of cytokeratin profiles and evolutionary analysis--a report from the kConFab Investigators.
|
18375895 |
2008 |
|
Hereditary Breast and Ovarian Cancer Syndrome
|
|
0.700 |
CausalMutation
|
CLINVAR |
Classifications within molecular subtypes enables identification of BRCA1/BRCA2 mutation carriers by RNA tumor profiling.
|
23704984 |
2013 |