rs4242382, None

N. diseases: 9
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.740 GeneticVariation BEFREE Blood samples from Finnish men were used to assess the risk of PCa related to three genetic variants (rs4242382, rs138213197, and rs200331695). 25683204 2015
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.740 GeneticVariation GWASCAT Two susceptibility loci identified for prostate cancer aggressiveness. 25939597 2015
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation BEFREE Blood samples from Finnish men were used to assess the risk of PCa related to three genetic variants (rs4242382, rs138213197, and rs200331695). 25683204 2015
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.740 GeneticVariation BEFREE Two correlated SNPs--rs10090154 and rs4242382--in Region 1 of chromosome 8q24, a prostate cancer susceptibility region, demonstrated statistically significant associations with colorectal cancer risk. 23935004 2014
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.740 GeneticVariation BEFREE The replicated data suggest that the 8q24 rs4242382-A variation might be associated with increased PCa susceptibility in Asian, Caucasian and African American populations. 25339022 2014
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation BEFREE The replicated data suggest that the 8q24 rs4242382-A variation might be associated with increased PCa susceptibility in Asian, Caucasian and African American populations. 25339022 2014
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation BEFREE Two correlated SNPs--rs10090154 and rs4242382--in Region 1 of chromosome 8q24, a prostate cancer susceptibility region, demonstrated statistically significant associations with colorectal cancer risk. 23935004 2014
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation GWASDB Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population. 23555315 2013
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation GWASDB Evaluating genetic risk for prostate cancer among Japanese and Latinos. 22923026 2012
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation BEFREE The ORs for a previously identified variant, rs4242382, and prostate cancer increased significantly (P<0.05) with exposure to the organophosphate insecticide fonofos, after correction for multiple testing, with per allele ORnonexposed of 1.17 (95% CI, 0.93-1.48), per allele OR(low) of 1.30 (95% CI, 0.75-2.27), and per allele ORhigh of 4.46 (95% CI, 2.17-9.17; P-interaction=0.002, adjusted P-interaction=0.02). 20978189 2010
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.740 GeneticVariation BEFREE The ORs for a previously identified variant, rs4242382, and prostate cancer increased significantly (P<0.05) with exposure to the organophosphate insecticide fonofos, after correction for multiple testing, with per allele ORnonexposed of 1.17 (95% CI, 0.93-1.48), per allele OR(low) of 1.30 (95% CI, 0.75-2.27), and per allele ORhigh of 4.46 (95% CI, 2.17-9.17; P-interaction=0.002, adjusted P-interaction=0.02). 20978189 2010
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation GWASDB Multiple loci identified in a genome-wide association study of prostate cancer. 18264096 2008
Malignant neoplasm of prostate
CUI: C0376358
Disease: Malignant neoplasm of prostate
0.740 GeneticVariation GWASDB Multiple newly identified loci associated with prostate cancer susceptibility. 18264097 2008
Prostate carcinoma
CUI: C0600139
Disease: Prostate carcinoma
0.740 GeneticVariation GWASCAT Multiple loci identified in a genome-wide association study of prostate cancer. 18264096 2008
Nasopharyngeal carcinoma
CUI: C2931822
Disease: Nasopharyngeal carcinoma
0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145 2010
Malignant neoplasm of colon and/or rectum
0.010 GeneticVariation BEFREE Two correlated SNPs--rs10090154 and rs4242382--in Region 1 of chromosome 8q24, a prostate cancer susceptibility region, demonstrated statistically significant associations with colorectal cancer risk. 23935004 2014
Multiple Chronic Conditions
CUI: C3266262
Disease: Multiple Chronic Conditions
0.010 GeneticVariation BEFREE 8q24 rs4242382 polymorphism is a risk factor for prostate cancer among multi-ethnic populations: evidence from clinical detection in China and a meta-analysis. 25339022 2014
Prostate cancer, familial
CUI: C2931456
Disease: Prostate cancer, familial
0.010 GeneticVariation BEFREE Assessing interactions of two loci (rs4242382 and rs10486567) in familial prostate cancer: statistical evaluation of epistasis. 24586834 2014
Colorectal Carcinoma
CUI: C0009402
Disease: Colorectal Carcinoma
0.010 GeneticVariation BEFREE Two correlated SNPs--rs10090154 and rs4242382--in Region 1 of chromosome 8q24, a prostate cancer susceptibility region, demonstrated statistically significant associations with colorectal cancer risk. 23935004 2014
Metastatic Prostate Carcinoma
CUI: C0936223
Disease: Metastatic Prostate Carcinoma
0.010 GeneticVariation BEFREE MSMB rs10993994 (per variant allele summary RR = 1.24, 95% CI = 1.05-1.48), 8q24 rs4242382 (RR = 1.40, 95% CI = 1.13-1.75), and 8q24 rs6983267 (RR = 0.67, 95% CI = 0.50-0.89) were associated with risk for metastatic prostate cancer. 21343373 2011
Metastasis from malignant tumor of prostate
0.010 GeneticVariation BEFREE MSMB rs10993994 (per variant allele summary RR = 1.24, 95% CI = 1.05-1.48), 8q24 rs4242382 (RR = 1.40, 95% CI = 1.13-1.75), and 8q24 rs6983267 (RR = 0.67, 95% CI = 0.50-0.89) were associated with risk for metastatic prostate cancer. 21343373 2011