rs4245739, MDM4

N. diseases: 21
Disease: Breast Carcinoma ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.730 GeneticVariation BEFREE Profile of the breast cancer susceptibility marker rs4245739 identifies a role for miRNAs. 29372105 2017
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.730 GeneticVariation BEFREE Interestingly, we observed a combinational effect between MDM4 rs4245739 and P53 Arg72Pro variants in attenuating breast cancer risk, highlighting the importance of the P53 tumor suppressor pathway genes during malignant transformation. 23793604 2013
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.730 GeneticVariation BEFREE However, our study failed to show any relationship between rs4245739 A>C and rs11801299 G>A variants and BC risk (P > .05). 29439926 2018
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.730 GeneticVariation GWASCAT Genome-wide association studies identify four ER negative-specific breast cancer risk loci. 23535733 2013
Breast Carcinoma
CUI: C0678222
Disease: Breast Carcinoma
0.730 GeneticVariation GWASCAT Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. 27117709 2016