|
Malignant neoplasm of breast
|
|
0.730 |
GeneticVariation
|
BEFREE |
However, our study failed to show any relationship between rs4245739 A>C and rs11801299 G>A variants and BC risk (P > .05).
|
29439926 |
2018 |
|
Breast Carcinoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
However, our study failed to show any relationship between rs4245739 A>C and rs11801299 G>A variants and BC risk (P > .05).
|
29439926 |
2018 |
|
Breast Carcinoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
Profile of the breast cancer susceptibility marker rs4245739 identifies a role for miRNAs.
|
29372105 |
2017 |
|
Malignant neoplasm of breast
|
|
0.730 |
GeneticVariation
|
BEFREE |
Profile of the breast cancer susceptibility marker rs4245739 identifies a role for miRNAs.
|
29372105 |
2017 |
|
Breast Carcinoma
|
|
0.730 |
GeneticVariation
|
GWASCAT |
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.
|
27117709 |
2016 |
|
Breast Carcinoma
|
|
0.730 |
GeneticVariation
|
BEFREE |
Interestingly, we observed a combinational effect between MDM4 rs4245739 and P53 Arg72Pro variants in attenuating breast cancer risk, highlighting the importance of the P53 tumor suppressor pathway genes during malignant transformation.
|
23793604 |
2013 |
|
Breast Carcinoma
|
|
0.730 |
GeneticVariation
|
GWASCAT |
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
23535733 |
2013 |
|
Malignant neoplasm of breast
|
|
0.730 |
GeneticVariation
|
GWASDB |
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
23535733 |
2013 |
|
Malignant neoplasm of breast
|
|
0.730 |
GeneticVariation
|
BEFREE |
Interestingly, we observed a combinational effect between MDM4 rs4245739 and P53 Arg72Pro variants in attenuating breast cancer risk, highlighting the importance of the P53 tumor suppressor pathway genes during malignant transformation.
|
23793604 |
2013 |
|
Prostate carcinoma
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
|
Malignant neoplasm of prostate
|
|
0.720 |
GeneticVariation
|
BEFREE |
This study is the first, to our knowledge, to demonstrate regulation of the MDM4 rs4245739 SNP C-allele by two miRNAs in prostate cancer, and thereby to identify a mechanism by which the MDM4 rs4245739 SNP A-allele may be associated with an increased risk for prostate cancer.
|
25670033 |
2015 |
|
Prostate carcinoma
|
|
0.720 |
GeneticVariation
|
BEFREE |
MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.
|
26471763 |
2015 |
|
Malignant neoplasm of prostate
|
|
0.720 |
GeneticVariation
|
BEFREE |
MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.
|
26471763 |
2015 |
|
Prostate carcinoma
|
|
0.720 |
GeneticVariation
|
BEFREE |
This study is the first, to our knowledge, to demonstrate regulation of the MDM4 rs4245739 SNP C-allele by two miRNAs in prostate cancer, and thereby to identify a mechanism by which the MDM4 rs4245739 SNP A-allele may be associated with an increased risk for prostate cancer.
|
25670033 |
2015 |
|
Malignant neoplasm of prostate
|
|
0.720 |
GeneticVariation
|
GWASDB |
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
|
23535732 |
2013 |
|
Prostate carcinoma
|
|
0.720 |
GeneticVariation
|
GWASCAT |
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.
|
23535732 |
2013 |
|
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
|
29455858 |
2018 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
|
27618452 |
2016 |
|
Diastolic blood pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.
|
27618452 |
2016 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, our analyses indicated that rs4245739 polymorphism in the M</span>DM4 gene may play an importan</span>t role in the etiology of cancer.
|
27742919 |
2016 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
These results indicate that the rs4245739 polymorphism may contribute to a decreased cancer susceptibility and support the hypothesis that genetic variants in the MDM4 genes act as important modifiers of cancer risk.
|
27738340 |
2016 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
These results indicate that the rs4245739 polymorphism may contribute to a decreased cancer susceptibility and support the hypothesis that genetic variants in the MDM4 genes act as important modifiers of cancer risk.
|
27738340 |
2016 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
Thus the MDM4 rs4245739 A > C polymorphism appears to be associated with decreased cancer risk.
|
27687591 |
2016 |
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
Thus the MDM4 rs4245739 A > C polymorphism appears to be associated with decreased cancer risk.
|
27687591 |
2016 |
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, our analyses indicated tha</span>t rs42</span>45739 polymorphism in the M</span>DM4 gene may play an importan</span>t role in the etiology of cancer.
|
27742919 |
2016 |