Crohn Disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
Among the TNFSF15 SNPs, rs4263839 associated with CD in Taiwan (P = 0.005), haplotype analysis did not increase the association.
|
24783249 |
2014 |
Crohn Disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that most of the seven TNFSF15 polymorphisms (except for rs4263839) were risk factors contributed to CD and UC susceptibility.
|
25028192 |
2014 |
Crohn Disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
The Crohn's disease risk allele rs4263839 G in the TNFSF15 gene was significantly associated with an increased risk of both IBS (p=2.2×10(-5); OR 1.37) and more pronouncedly, IBS-C (p=8.7×10(-7); OR 1.79) in the entire sample.
|
21636646 |
2011 |
Crohn Disease
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
Crohn Disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
|
18587394 |
2008 |
Multiple Sclerosis
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
Asthma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.
|
21150878 |
2011 |
Irritable Bowel Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
Ten relevant genes were evaluated.SNPs rs4263839 and rs6478108 of TNFSF15 associated with an increased risk of IBS; IL6 rs1800795 increased the risk for Caucasian IBS patients which diagnosed by Rome III criteria; and IL23R rs11465804 increased the risk for IBS-C patients.
|
31615448 |
2019 |
Irritable Bowel Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our meta-analysis could not confirm a major role of most investigated SNPs, but a moderate association between rs4263839 TNFSF15 and IBS, in particular IBS-C.
|
25824902 |
2015 |
Irritable Bowel Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
The Crohn's disease risk allele rs4263839 G in the TNFSF15 gene was significantly associated with an increased risk of both IBS (p=2.2×10(-5); OR 1.37) and more pronouncedly, IBS-C (p=8.7×10(-7); OR 1.79) in the entire sample.
|
21636646 |
2011 |
Diverticulitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
A second haplotype, rs6478108 (A), rs6478109 (G), rs7869487 (A), and rs4263839 (G), was also associated with DD in this cohort (P = 0.025).
|
28624054 |
2017 |
Ulcerative Colitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
This meta-analysis indicated that most of the seven TNFSF15 polymorphisms (except for rs4263839) were risk factors contributed to CD and UC susceptibility.
|
25028192 |
2014 |
Constipation
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Crohn's disease risk allele rs4263839 G in the TNFSF15 gene was significantly associated with an increased risk of both IBS (p=2.2×10(-5); OR 1.37) and more pronouncedly, IBS-C (p=8.7×10(-7); OR 1.79) in the entire sample.
|
21636646 |
2011 |