Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
The SNPs rs2075650 and rs4420638 were linked to the most replications within a single reclassified phenotype or very similar reclassified phenotypes; both were associated with Alzheimer's disease (AD).
|
29942042 |
2019 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
The minor allele of rs4420638 (G) and the minor allele of rs157582 (T) showed associations with lower Mini-mental State Examination score, higher Alzheimer Disease Assessment Scale-cognitive subscale 11 score and smaller entorhinal volume using both baseline and longitudinal measurements, as well as with accelerated cognitive decline.
|
31760383 |
2019 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities.
|
30636644 |
2019 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases.
|
27790247 |
2016 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
Our case-control study shows that rs4420638 genotype AA has a significant association with the concentrations of circulating HDL-C and APOA-I in CHD in Han Chinese males.
|
26535656 |
2015 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of age-at-onset in Alzheimer's disease.
|
22005931 |
2012 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study of Alzheimer's disease.
|
22832961 |
2012 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Genome-wide association study of Alzheimer's disease.
|
22832961 |
2012 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association analysis of age-at-onset in Alzheimer's disease.
|
22005931 |
2012 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.
|
21347282 |
2011 |
Coronary heart disease
|
|
0.820 |
GeneticVariation
|
BEFREE |
SNPs rs6700896 in LEPR (OR, 1.06; 95% CI, 1.02 to 1.09; per minor allele), rs4537545 in IL6R (OR, 0.94; 95% CI, 0.91 to 0.97), and rs4420638 in the APOE-CI-CII cluster (OR, 1.16; 95% CI, 1.12 to 1.21) were all associated with risk of coronary heart disease.
|
19567438 |
2009 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Sorl1 as an Alzheimer's disease predisposition gene?
|
17975299 |
2008 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
|
17998437 |
2008 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Sorl1 as an Alzheimer's disease predisposition gene?
|
17975299 |
2008 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
|
17998437 |
2008 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASCAT |
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
|
17474819 |
2007 |
Alzheimer's Disease
|
|
0.820 |
GeneticVariation
|
GWASDB |
A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.
|
17474819 |
2007 |
Age related macular degeneration
|
|
0.810 |
GeneticVariation
|
BEFREE |
Nineteen single nucleotide polymorphisms (SNPs) previously associated with AMD, including rs10490924 (<i>ARMS2/HTRA1</i>), rs10737680 (<i>CFH</i>), rs13278062 (<i>TNFRSF10A</i>), rs1864163 (<i>CETP</i>), rs2230199 (<i>C3</i>), rs3130783 (<i>IER3/DDR1</i>), rs334353 (<i>TGFBR1</i>), rs3812111 (<i>COL10A1</i>), rs429608 (<i>C2/CFB</i>), rs4420638 (<i>APOE</i>), rs4698775 (<i>CFI</i>), rs5749482 (<i>TIMP3</i>), rs6795735 (<i>ADAMTS9</i>), rs8017304 (<i>RAD51B</i>), rs8135665 (<i>SLC16A8</i>), rs920915 (<i>LIPC</i>), rs943080 (<i>VEGFA</i>), rs9542236 (<i>B3GALTL</i>) and rs13081855 (<i>COL8A1/FILIP1L</i>), were genotyped in this cohort.
|
31819893 |
2019 |
Age related macular degeneration
|
|
0.810 |
GeneticVariation
|
GWASDB |
Seven new loci associated with age-related macular degeneration.
|
23455636 |
2013 |
Age related macular degeneration
|
|
0.810 |
GeneticVariation
|
GWASCAT |
Seven new loci associated with age-related macular degeneration.
|
23455636 |
2013 |
High density lipoprotein measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |
Low density lipoprotein cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
|
30926973 |
2019 |