rs4570625, TPH2

N. diseases: 25
Disease: Panic Disorder ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Panic Disorder
CUI: C0030319
Disease: Panic Disorder
0.020 GeneticVariation BEFREE In this study involving 64 individuals, we examined the associations between prefrontal cortical GABA concentration and 12 single nucleotide polymorphisms (SNPs) spanning the TPH2 gene, including rs4570625 (-703 G/T SNP), a potentially functional TPH2 polymorphism that has been associated with decreased TPH2 mRNA expression and panic disorder. 23552096 2013
Panic Disorder
CUI: C0030319
Disease: Panic Disorder
0.020 GeneticVariation BEFREE Moreover, rs4570625 may have a gender-dependent effect on susceptibility to PD. 19132526 2009