rs4646437, CYP3A4

N. diseases: 8
Disease: Hypertensive disease ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.020 GeneticVariation BEFREE The A allele of <i>CYP3A4</i> rs4646437 was associated with an increased risk for hypert</span>ension</span> (<i>OR</i>=1.36, 95% CI: 1.12-1.66, <i>P</i>=0.002). 30910847 2019
Hypertensive disease
CUI: C0020538
Disease: Hypertensive disease
0.020 GeneticVariation BEFREE In conclusion, hypertension is more likely to occur in A-allele carriers of the CYP3A4 rs4646437 variant in our cohort of mRCC patients treated with sunitinib. 26810136 2017