|
Coronary Artery Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our data demonstrated that rs4673 transition may be involved in susceptibility to CAD and could be applied as a potential biomarker for this disease.
|
28474233 |
2017 |
|
Coronary Artery Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
The C242T polymorphism of p22phox gene (rs4673) has been linked to the reduced coronary artery disease (CAD) risk, but results in the published literatures are controversial.
|
20100625 |
2010 |
|
Coronary Artery Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Multivariate logistic regression analysis with adjustment for age, body mass index, and the prevalence of smoking, hypertension, diabetes mellitus, and hyperuricemia revealed that three polymorphisms [994G --> T (Val279Phe) in the platelet-activating factor acetylhydrolase gene, 242C --> T (His72Tyr) in the NADH/NADPH oxidase p22 phox gene, and 1100C --> T in the apolipoprotein C-III gene] were significantly associated with CAD in men with hypercholesterolemia.
|
14709372 |
2004 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
According to the results of cross-sectional study, the tested polymorphism of the NADPH oxidase P22phox gene (rs4673) was found to be associated with the development of AH, indicating that the oxidative stress gene NADPH oxidase might be implicated in the pathogenesis of AH in subjects with type 2 diabetes.
|
23701472 |
2014 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.020 |
GeneticVariation
|
BEFREE |
A number of epidemiological studies have explored the association between NAD(P)H oxidase P22 phox gene C242T (rs4673) polymorphism and susceptibility to type 2 diabetes mellitus (T2DM), but the results are still debatable.
|
24156725 |
2014 |
|
Diabetic peripheral neuropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
We showed a strong association of the CYBA polymorphism rs4673 with DPN in Slovak children and adolescents with T1D.
|
29924645 |
2018 |
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
We showed a strong association of the CYBA polymorphism rs4673 with DPN in Slovak children and adolescents with T1D.
|
29924645 |
2018 |
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
<i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer.
|
28529598 |
2017 |
|
Carcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
The roles of interleukin 8 (<i>IL8</i>) rs4073, nuclear factor kappa B (<i>NF</i>κ<i>B</i>) rs28362491, cytochrome b-245, alpha polypeptide (<i>CYBA</i>) rs4673, <i>NAD(P) H</i> dehydrogenase, quinone 1 (<i>NQO1</i>) rs1800566, nitric oxide synthase 2 and inducible (<i>NOS2</i>) rs2297518 polymorphisms in lung carcinogenesis were investigated.
|
28529598 |
2017 |
|
Coronary heart disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis.
|
28474233 |
2017 |
|
Chronic granulomatous disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.
|
29132304 |
2017 |
|
Peroxisome Biogenesis Disorder, Complementation Group D
|
|
0.010 |
GeneticVariation
|
BEFREE |
The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.
|
29132304 |
2017 |
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association analysis of rs1049255 and rs4673 transitions in p22phox gene with coronary artery disease: A case-control study and a computational analysis.
|
28474233 |
2017 |
|
Primary malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
<i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer.
|
28529598 |
2017 |
|
Carcinoma of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
<i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer.
|
28529598 |
2017 |
|
Granulomatous Disease, Chronic, X-Linked
|
|
0.010 |
GeneticVariation
|
BEFREE |
The three CYBA variants (rs4673, rs1049254 and rs1049255) are benign: new evidence from a patient with CGD.
|
29132304 |
2017 |
|
Macroalbuminuric diabetic nephropathy
|
|
0.010 |
GeneticVariation
|
BEFREE |
The p22phox C242T gene polymorphism (rs4673) may be linked to an increased susceptibility for overt diabetic nephropathy (ODN), but the study results are still inconclusive.
|
27926811 |
2017 |
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
According to the results of cross-sectional study, the tested polymorphism of the NADPH oxidase P22phox gene (rs4673) was found to be associated with the development of AH, indicating that the oxidative stress gene NADPH oxidase might be implicated in the pathogenesis of AH in subjects with type 2 diabetes.
|
23701472 |
2014 |
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using a retrospective case-control design, we evaluated cardiac histological lesions and NADPH genotype (polymorphisms rs1883112, rs4673, and rs13058338) in 97 consecutive decedents with a cancer diagnosis (48 treated with anthracyclines).
|
23576480 |
2013 |
|
Cardiac fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients receiving anthracyclines, NADPH oxidase polymorphism rs4673 protected against focal myocardial necrosis (odds ratio [OR], 0.11; 95% confidence interval [CI], 0.20-0.63) whereas rs1883112 was strongly associated with cardiac fibrosis (OR, 5.11; 95% CI, 1.59-16.43), which was present in all homozygotes.
|
23576480 |
2013 |
|
Sudden sensorineural hearing loss
|
|
0.010 |
GeneticVariation
|
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using a retrospective case-control design, we evaluated cardiac histological lesions and NADPH genotype (polymorphisms rs1883112, rs4673, and rs13058338) in 97 consecutive decedents with a cancer diagnosis (48 treated with anthracyclines).
|
23576480 |
2013 |
|
Meniere Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |
|
Myocardial necrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients receiving anthracyclines, NADPH oxidase polymorphism rs4673 protected against focal myocardial necrosis (odds ratio [OR], 0.11; 95% confidence interval [CI], 0.20-0.63) whereas rs1883112 was strongly associated with cardiac fibrosis (OR, 5.11; 95% CI, 1.59-16.43), which was present in all homozygotes.
|
23576480 |
2013 |
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
In patients receiving anthracyclines, NADPH oxidase polymorphism rs4673 protected against focal myocardial necrosis (odds ratio [OR], 0.11; 95% confidence interval [CI], 0.20-0.63) whereas rs1883112 was strongly associated with cardiac fibrosis (OR, 5.11; 95% CI, 1.59-16.43), which was present in all homozygotes.
|
23576480 |
2013 |