rs4680, COMT;MIR4761

N. diseases: 249
Disease: Irritable Bowel Syndrome ×
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.030 GeneticVariation BEFREE COMT Val158Met Polymorphism and Symptom Improvement Following a Cognitively Focused Intervention for Irritable Bowel Syndrome. 28252569 2017
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.030 GeneticVariation BEFREE In a regression model, the number of methionine alleles in COMT val158met was linearly related to placebo response as measured by changes in IBS-SSS (p = .035). 23110189 2012
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.030 GeneticVariation BEFREE In this study we found an association between the val/val genotype of the val158met COMT gene and IBS as well as to specific IBS related bowel pattern in IBS patients. 21437260 2011