rs4680, COMT;MIR4761

N. diseases: 155
Source: ALL
Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE The effects of the catechol-O-methyltransferase val158met polymorphism on white matter connectivity in patients with panic disorder. 23141115 2013
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE A significant relationship was found between the COMT Val158Met polymorphism and PD. 22036916 2012
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE Sympathetic nervous function and the effect of the catechol-O-methyltransferase Val(158)Met polymorphism in patients with panic disorder. 19900710 2010
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE Only Val158Met polymorphism of the catechol-O-methyltransferase gene has been implicated in susceptibility to PD by several studies in independent samples and confirmed in a recent meta-analysis. 20048750 2010
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE Meta-analysis of COMT val158met in panic disorder: ethnic heterogeneity and gender specificity. 17357147 2007
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women. 15009906 2004
PANIC DISORDER 1
CUI: C1868649
Disease: PANIC DISORDER 1
0.070 GeneticVariation BEFREE A well-characterized single nucleotide polymorphism (472G/A-Val/Met-SNP8) in the coding sequence of the catechol-O-methyltransferase (COMT) gene leads to a three- to fourfold difference in enzymatic activity and clinical and animal studies suggest a role in anxiety states like panic disorder. 11950461 2002