rs4722999, CRHR2

N. diseases: 5
Source: ALL
Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
Borderline Personality Disorder
CUI: C0006012
Disease: Borderline Personality Disorder
0.010 GeneticVariation BEFREE Two FKBP5 alleles (rs3798347-T and rs10947563-A) were more frequent in BPD subjects with history of physical abuse and emotional neglect and two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD subjects with sexual and physical abuse. 26182893 2016
Drug abuse
CUI: C0013146
Disease: Drug abuse
0.010 GeneticVariation BEFREE Two FKBP5 alleles (rs3798347-T and rs10947563-A) were more frequent in BPD subjects with history of physical abuse and emotional neglect and two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD subjects with sexual and physical abuse. 26182893 2016
Emotional neglect
CUI: C4296683
Disease: Emotional neglect
0.010 GeneticVariation BEFREE Two FKBP5 alleles (rs3798347-T and rs10947563-A) were more frequent in BPD subjects with history of physical abuse and emotional neglect and two CRHR2 variants (rs4722999-C and rs12701020-C) in BPD subjects with sexual and physical abuse. 26182893 2016
Irritable Bowel Syndrome
CUI: C0022104
Disease: Irritable Bowel Syndrome
0.010 GeneticVariation BEFREE We found that rs4722999 and rs3779250, located in intronic region, were associated with IBS in terms of genotype frequency (rs4722999: P = 0.037; rs3779250: P = 0.017) and that the distribution of the major allele was significantly different between patients and controls. 26808377 2016
Panic Disorder
CUI: C0030319
Disease: Panic Disorder
0.010 GeneticVariation BEFREE The C-C haplotype consisting of rs4722999 and rs37790 in CRHR1 was associated with PD. 22467522 2012